Phentermine Weight Loss Pill

About The Phentermine Weight Loss Pill

Phentermine weight loss pill

Phentermine Weight Loss Pill Overview

Phentermine (Adipex-P), an amphetamine derivative, is the most prescribed weight loss medication in the United States that is used in combination with a weight loss program that utilizes  diet plans for weight loss. Available as a low cost generic, phentermine has been approved for weight loss since 1973. Ask a weight loss doctor about their experiences with Phentermine weight loss pills and how they can help you lose weight fast.

Here are the great questions we hear from my patients over and over:

  1. How does phentermine work? Phentermine increases release of neurotransmitters which simulate metabolism and suppress appetite. Phentermine is a “sympathomimetic” because it simulates the release and inhibition of certain neurotransmitters in your brain. Essentially it tricks your mind into feeling full!
  2. Release of which neurotransmitters? A large body of evidence has observed that the phentermine weight loss pill works by causing the release of two neurotransmitters, dopamine and norepinephrine, in your brain to suppress hunger.
  3. Wait, wasn’t this the scary fen-phen drug? Kind of. Here is the story: fen-phen was a mixture of fenfluramine (the “fen”) and phentermine (the “phen”). The fen-phen combination was very popular in 1996, with 6.6 million prescriptions dispensed in the US. Soon after, reports of heart valve disease and primary pulmonary hypertension were reported, caused by fenfluramine (the “fen” part of the drug). In September 1997, the FDA recommended that fenfluramine be withdrawn and that patients should immediately stop taking it. So don’t worry, phentermine was not part of these warnings and has not been shown to contribute to heart valve disease or any lung problems.
  4. What is the difference between phentermine, cocaine, and amphetamines? A lot. While it is true that they are all considered sympathomimetics, the addictive effects of cocaine and methamphetamines do not exist with phentermine. This is because cocaine and methamphetamines are much more potent releasers of norepinephrine and dopamine, which cause users to experience the addictive effects. 
  5. Who should not take phentermine? Phentermine is not a good idea in patients with coronary heart disease, uncontrolled high blood pressure, hyperthyroidism, or in patients with a history of drug abuse.
  6. Why is phentermine a “scheduled” drug like Xanax, Ativan or Ambien? The Phentermine weight loss pill is a schedule IV drug, which suggests the potential for abuse, although the actual potential is low. If you are concerned, talk to your doctor about the potential for addictive effects.
  7. How much weight will I loose with phentermine? Phentermine 37.5mg daily for 12 weeks leads to an average weight loss of 15.8 pounds (7.2 kgs).
  8. Will phentermine give me side effects? Dry mouth is the one i hear most often from my patients, and it doesn’t seem to bother them. The Phentermine weight loss pill can also cause increased head rate, blood pressure, insomnia, constipation and nervousness. So keep an eye on your blood pressure if you do decide to start on it.

Can The Phentermine Weight Loss Pill Help With Certain Eating Disorders?

The combination of phentermine and topiramate may help reduce binge eating in people with binge eating disorder (BED) and bulimia nervosa.

BED is characterized by eating large amounts of food, often quickly and to the point of discomfort. It’s also associated with a feeling of losing control during the binge, as well as feelings of shame or guilt afterward. Bulimia nervosa involves the same binge-eating behavior as with BED, but includes behaviors, such as self-induced vomiting, in an attempt to compensate for the effects of binge eating 

In a small 12-week study in obese or overweight people with BED, the phentermine and topiramate drug combination was associated with significant reductions in weight, BMI, and binge-eating episode frequency. In another 12-week study, people with BED or bulimia nervosa were randomized to receive the drug combination or a placebo. Over 28 days, treatment with the phentermine and topiramate combination decreased the participants’ number of binge-eating days from 16.2 to 4.2. The same results were not observed in the placebo group.

By reducing binging episodes, the drug combination may help the estimated 40–80% of people with BED or bulimia nervosa who are overweight/obese lose weight while improving mood and a sense of control with eating.

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